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Reprinted from Pharmacology Biochemistry & Behavior, v. 21, Suppl., 1, by A. Keith Brewer, Ph.D., "The High pH Therapy for Cancer, Tests on Mice and Humans," pp. 1-5, Copyright 1984, with permission from Elsevier Science. Single copies of the article can be downloaded and printed for the reader's personal research and study.


The High pH Therapy for Cancer
Tests on Mice and Humans

  A. KEITH BREWER, Ph.D.
A.. Keith Brewer Science Library, 325 N. Central Ave., Richland Center, WI 53581

HIGH AND LOW pH THERAPIES

Only two therapies will be mentioned here. Both are apparently effective. These are the Low pH therapy devised by Von Ardenne et al. [23-25] and the High pH therapy developed by the writer.

The Low pH Therapy

In this therapy devised by Von Ardenne, glucose is injected into the blood stream. As a consequence, the cancer cell pH will drop eventually to the 5.5 range. The patient is then placed in a furnace heated to 104 degrees Fahrenheit for a matter of hr [23-25]. The older the patient, the fewer the number of hours. The patient is allowed to breathe cold air. Diathermy is also applied over the tumor area which, in the absence of a blood supply, will cause the temperature of the mass to rise to something over 106 degrees Fahrenheit. At these high temperatures and in the acid medium, the life of cancer cells is very short. The only drawback to the therapy is that a case of severe toxemia may result from the out-leakage of the acid toxins within the tumor masses [23-25].

The High pH Therapy

The ready uptake of cesium and rubidium by the cancer cells lead the writer to the High pH therapy. This consists of feeding the patient close to 6 g of CsCl or RbCl per day in conjunction with the administration of ascorbic and retionic acids, Vitamins C and A, which being weak acids, upon absorption by the tumor cells will enhance the negative potential gradient across the membrane, and also zinc and selenium salts which, when absorbed on the membrane surface, will act as broad and moderately strong electron donors. Both types of compounds have been shown in mice to drastically enhance the pickup for cesium and rubidium ions.

The toxic dose for CsCl is 135 g. The administration of 6 g per day therefore has no toxic effects. It is sufficient however to give rise to the pH in the cancer cells, bringing them up in a few days to the 8 or above where the life of the cell is short. In addition, the presence of Cs and Rb salts in the body fluids neutralizes the acid toxins leaking out of the tumor mass and renders them nontoxic.

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